How Long Does Hydrocodone Stay in Your System?
Medically Reviewed by Dr. Michael Ferri
October 18, 2024
Table of Contents
Hydrocodone is a powerful prescription opioid used to manage moderate to severe pain. While effective in providing relief, it is the most commonly prescribed opioid in the United States. Its potential for misuse and addiction is a growing concern.
Hydrocodone is most commonly used for chronic pain by activating opioid receptors, which can lead to euphoria, stress reduction, tiredness, and dizziness.
The duration of how long hydrocodone stays in your system is dependent on several factors and can vary from person to person. However due to it’s highly addictive properties, understanding how long hydrocodone stays in your system is vital to proper healthcare and adequately managing chronic pain.
If you or a loved one are suffering from Hydrocodone addiction, Music City Detox offers multiple detox programs in Nashville.
How Hydrocodone Works
Hydrocodone is prescribed orally, and typically takes an hour to provide symptom relief. The drug works by binding to opioid receptors in the brain and spinal cord, altering the way the body perceives pain.
It triggers the release of dopamine, a neurotransmitter responsible for feelings of pleasure and reward, which contributes to its pain-relieving effects.
Unfortunately, this also creates a euphoric “high” that can lead to misuse and dependency over time. Hydrocodone is often combined with other pain relievers, such as acetaminophen, to enhance its effectiveness. The pain relief mechanism can also heighten the risk of addiction.
How Long Does Hydrocodone Last?
The effects of hydrocodone typically start within 30 to 60 minutes after ingestion, providing pain relief for about 4 to 6 hours.
Extended-release formulations of hydrocodone may provide relief for up to 12 hours. However, the duration of its effects can vary depending on several factors, including the individual’s metabolism, dosage, and frequency of use.
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How Long Does Hydrocodone Stay in Your System?
Hydrocodone remains detectable in the body for varying lengths of time depending on the type of drug test used. Here’s a breakdown of how long hydrocodone stays in your system dependent on multiple different drug tests:
- Urine Test: Hydrocodone can be detected in urine for up to 2-4 days after the last dose.
- Blood Test: In the bloodstream, hydrocodone is detectable for up to 24 hours.
- Saliva Test: Hydrocodone can be detected in saliva for up to 36 hours after use.
- Hair Test: A hair follicle test can detect hydrocodone for up to 90 days after the last dose.
The exact timeframe can vary based on factors like the individual’s age, weight, metabolism, liver function, and the dosage taken.
Understanding Hydrocodone Withdrawal
Hydrocodone withdrawal can be an uncomfortable and challenging process, particularly for individuals who have been using the drug for an extended period.
Withdrawal symptoms may start as early as 6 to 12 hours after the last dose and peak within 48 to 72 hours. Common symptoms of hydrocodone withdrawal include:
- Anxiety and irritability
- Muscle aches
- Sweating and chills
- Nausea and vomiting
- Insomnia
- Cravings for the drug
The severity of these symptoms can vary depending on how long hydrocodone was used, the dosage, and the individual’s overall health.
In some cases, withdrawal symptoms can persist for weeks, making medical detox and treatment crucial for a successful and sustainable recovery.
Treatment Options for Hydrocodone Dependence
If you or a loved one is struggling with hydrocodone dependence or addiction, several treatment options are available to help you safely detox and begin the journey to recovery:
- Detox: Medically supervised detox is often the first and necessary step in treating hydrocodone addiction. During detox, a team of medical and behavioral healthcare professionals can manage withdrawal symptoms and provide medications to ease discomfort, ensuring the process is as safe and comfortable as possible.
- Inpatient Rehab: Inpatient rehab is a step-down level of care after detox, and provides 24/7 care in a structured environment. Inpatient rehab is ideal for individuals who require intensive support away from distractions. Inpatient programs often include therapy, group counseling, and holistic treatments to address both the physical and psychological aspects of addiction.
- Dual Diagnosis Treatment: Many people struggling with hydrocodone addiction also have underlying mental health issues such as anxiety or depression. Dual diagnosis treatment addresses both the substance use disorder and any co-occurring mental health conditions, offering a more comprehensive approach to recovery.