Hydrocodone vs Oxycodone: What's The Difference?
Table of Contents
Medically Reviewed by Dr. Michael Ferri
Last Updated on:
August 14, 2024
Hydrocodone and oxycodone are two of the most commonly prescribed opioid medications used for pain management.
Both are effective at relieving moderate to severe pain, but they also carry significant risks, including the potential for addiction. While these medications are similar, they have distinct differences in their chemical structure, usage, side effects, and potential for abuse. Understanding these differences is crucial to ensure safe and effective treatment.
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What Is Hydrocodone?
Hydrocodone is a semi-synthetic opioid derived from codeine, commonly used to treat moderate to severe pain. It’s often prescribed in combination with other medications like acetaminophen, as seen in products like Vicodin and Norco.
Hydrocodone works by binding to the opioid receptors in the brain and spinal cord, altering the perception of pain and providing relief. Due to its effectiveness, hydrocodone is one of the most prescribed pain relievers in the United States.
What Is Oxycodone?
Oxycodone is another semi-synthetic opioid, but it is derived from thebaine, an alkaloid found in the opium poppy. Like hydrocodone, oxycodone is used to manage moderate to severe pain, often after surgeries or injuries. It is available in both immediate-release and extended-release formulations, and it can be prescribed alone (as in OxyContin) or in combination with other pain relievers (like Percocet, which combines oxycodone with acetaminophen). Oxycodone is known for its potent pain-relieving properties, making it a popular choice for managing chronic pain.
Hydrocodone vs Oxycodone
While both hydrocodone and oxycodone are powerful pain relievers, there are key differences between the two. Chemically, oxycodone is slightly stronger than hydrocodone, meaning it may require a lower dose to achieve the same level of pain relief. However, this also means that oxycodone has a higher potential for abuse and addiction.
When it comes to effectiveness, some studies suggest that oxycodone may provide more potent pain relief, particularly for severe pain, while hydrocodone is often used for less intense pain. However, the choice between the two ultimately depends on the patient’s specific condition, pain severity, and how they respond to each medication.
Side Effects of Hydrocodone vs Oxycodone
Both hydrocodone and oxycodone share similar side effects due to their opioid nature. Common side effects include:
- Drowsiness
- Nausea and vomiting
- Constipation
- Dizziness
- Respiratory depression
However, there are some differences in how these side effects may manifest. For instance, oxycodone is more likely to cause dizziness, while hydrocodone may have a higher likelihood of causing constipation. Additionally, due to oxycodone’s potency, the risk of respiratory depression is slightly higher, especially in higher doses or when combined with other central nervous system depressants.
Hydrocodone vs Oxycodone: When Does It Become Addiction?
Both hydrocodone and oxycodone have a high potential for addiction due to their ability to produce feelings of euphoria in addition to pain relief. Addiction can develop when these medications are used for longer periods or at higher doses than prescribed. Signs of addiction include cravings, inability to control use, and continuing to use the medication despite negative consequences.
The risk of addiction is present even when these drugs are used as prescribed, making it essential for patients and healthcare providers to monitor usage closely. Oxycodone, due to its higher potency, may lead to addiction more quickly than hydrocodone.
Getting Help For Opioid Use Disorder
If you or someone you know is struggling with addiction to hydrocodone, oxycodone, or any other opioid, it’s crucial to seek help as soon as possible. Opioid use disorder is a serious condition, but with the right treatment, recovery is possible.
Treatment options include Medication-Assisted Treatment (MAT), behavioral therapy, and support groups. MAT, which combines medications like Vivitrol or Naltrexone with counseling and behavioral therapies, is particularly effective in managing withdrawal symptoms and reducing cravings.
If you or a loved one is struggling, Music City Detox can help. Call us now at 615-695-1009 or verify your insurance.